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Article

Association of prescription data with clinical manifestations and polygenic risk scores in patients with bipolar I disorder: An exploratory study.

Journal of affective disorders - 15 Dec 2024

Park Young-Min, Lee Bun-Hee, Shekhtman Tatyana, Kelsoe John R

Abstract excerpt

BACKGROUND: We assessed the association of prescription data with clinical manifestations and polygenic risk scores (PRS) in patients with bipolar I disorder. METHODS: We enrolled 1471 individuals with BID and divided them into several groups according to treatment options and clinical manifestations. BD-PRS of each patient was calculated using the Psychiatric Genomics Consortium data. Data on single nucleotide...

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PMID: 39142578
DOI: 10.1016/j.jad.2024.08.039

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