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Article

EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway

17 Mar 2023

Abstract excerpt

BACKGROUND: The prognosis of pancreatic cancer patients remains relatively poor. Although some patients would receive surgical resection, distant metastasis frequently occurs within one year. Epithelial-mesenchymal transition (EMT), as a pathological mechanism in cancer progression, contributed to the local and distant metastasis of pancreatic cancer. METHODS: Tissue microarray analysis and immunohistochemistry...

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PMID: 36932397
DOI: 10.1186/s12967-023-04043-4

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