Article

RNA binding protein Pumilio2 promotes chemoresistance of pancreatic cancer via focal adhesion pathway and interacting with transcription factor EGR1

2024-11-20

Abstract excerpt

<title>Abstract</title> <p>Background Pancreatic cancer (PC) has insidious onset, high malignancy and poor prognosis. Gemcitabine (GEM) is one of the first-line chemotherapy drugs for PC. However, resistance for GEM has always been a bottleneck problem leading to recurrence and death of PC patients. RNA-binding proteins (RBPs) are a kind of important proteins that regulate transportation, splicing, stability and...

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Literature Corpus work: 45b8f266-c467-58be-a16d-4eed83be7e8e
DOI: 10.21203/rs.3.rs-5312328/v1

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