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Article

Adoption of Universal Testing in Endometrial Cancers for Microsatellite Instability Using Next-Generation Sequencing.

JCO precision oncology - 1 Sept 2023

Rodriguez Isabel V, Strickland Sarah, Wells David, Manhardt Enna, Konnick Eric Q, Garcia Rochelle, Swisher Elizabeth, Kilgore Mark, Norquist Barbara

Abstract excerpt

PURPOSE: To assess implementation of a next-generation sequencing (NGS) assay to detect microsatellite instability (MSI) as a screen for Lynch syndrome (LS) in endometrial cancer (EC), while determining and comparing characteristics of the four molecular subtypes. METHODS: A retrospective review was performed of 408 total patients with newly diagnosed EC: 140 patients who underwent universal screening with NGS...

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37856764
DOI: 10.1200/PO.23.00033
PMCID: PMC10861015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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