Article
Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study.
Neurobiology of disease - 1 Apr 2023
Premi Enrico, Pengo Marta, Mattioli Irene, Cantoni Valentina, Dukart Juergen, Gasparotti Roberto, Buratti Emanuele, Padovani Alessandro, Bocchetta Martina, Todd Emily G, Bouzigues Arabella, Cash David M, Convery Rhian S, Russell Lucy L, Foster Phoebe, Thomas David L, van Swieten John C, Jiskoot Lize C, Seelaar Harro, Galimberti Daniela, Sanchez-Valle Raquel, Laforce Robert, Moreno Fermin, Synofzik Matthis, Graff Caroline, Masellis Mario, Tartaglia Maria Carmela, Rowe James B, Tsvetanov Kamen A, Vandenberghe Rik, Finger Elizabeth, Tiraboschi Pietro, de Mendonça Alexandre, Santana Isabel, Butler Chris R, Ducharme Simon, Gerhard Alexander, Levin Johannes, Otto Markus, Sorbi Sandro, Le Ber Isabelle, Pasquier Florence, Rohrer Jonathan D, Borroni Barbara
Abstract excerpt
BACKGROUND: Neurotransmitters deficits in Frontotemporal Dementia (FTD) are still poorly understood. Better knowledge of neurotransmitters impairment, especially in prodromal disease stages, might tailor symptomatic treatment approaches. METHODS: In the present study, we applied JuSpace toolbox, which allowed for cross-modal correlation of Magnetic Resonance Imaging (MRI)-based measures with nuclear imaging...
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