Article
Frequency and Longitudinal Course of Behavioral and Neuropsychiatric Symptoms in Participants With Genetic Frontotemporal Dementia.
Neurology - 22 Oct 2024
Schönecker Sonja, Martinez-Murcia Francisco J, Denecke Jannis, Franzmeier Nicolai, Danek Adrian, Wagemann Olivia, Prix Catharina, Wlasich Elisabeth, Vöglein Jonathan, Loosli Sandra V, Brauer Anna, Górriz Sáez Juan-Manuel, Bouzigues Arabella, Russell Lucy L, Foster Phoebe H, Ferry-Bolder Eve, van Swieten John C, Jiskoot Lize C, Seelaar Harro, Sanchez-Valle Raquel, Laforce Robert, Graff Caroline, Galimberti Daniela, Vandenberghe Rik, de Mendonça Alexandre, Tiraboschi Pietro, Santana Isabel, Gerhard Alexander, Sorbi Sandro, Otto Markus, Pasquier Florence, Ducharme Simon, Butler Christopher, Le Ber Isabelle, Finger Elizabeth, Tartaglia Maria Carmela, Masellis Mario, Rowe James B, Synofzik Matthis, Moreno Fermin, Borroni Barbara, Rohrer Jonathan D, Priller Josef, Höglinger Günter U, Levin Johannes
Abstract excerpt
BACKGROUND AND OBJECTIVES: Behavioral and neuropsychiatric symptoms are frequent in patients with genetic frontotemporal dementia (FTD). We aimed to describe behavioral and neuropsychiatric phenotypes in genetic FTD, quantify their temporal association, and investigate their regional association with brain atrophy. METHODS: We analyzed data of pathogenic variant carriers in the chromosome 9 open reading frame 72...
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