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Article

The protean role of Val804Met RET mutation in thyroid neoplasms: An example of a "MEN2C" syndrome?

Pathology, research and practice - 1 Apr 2023

Miani Cesare, Locatello Luca Giovanni, Rugiu Maria Gabriella, Antonio Jamile Karina, Di Loreto Carla, Pegolo Enrico

Abstract excerpt

BACKGROUND: Val804Met RET is one of the most common genetic alterations in Multiple Endocrine Neoplasia 2 and is considered to confer only a moderate risk for familial medullary thyroid carcinoma (MTC). The associated phenotype can however be much more complex in some cases. METHODS: A clinical, genetic, and pathological analysis was conducted on a family cluster of thyroid neoplasms associated with Val804Met RET...

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Share to Adrenal Gland Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36889173
DOI: 10.1016/j.prp.2023.154388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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