Article
Infant blood concentrations of folate markers and catabolites are modified by 5,10-methylenetetrahydrofolate reductase C677T genotype and dietary folate source.
The American journal of clinical nutrition - 1 Mar 2023
Obeid Rima, Warnke Ines, Wittke Anja, Bendik Igor, Troesch Barbara, Schoop Rotraut, Hecht Christina, Demmelmair Johann, Koletzko Berthold
Abstract excerpt
BACKGROUND: Folate intake and polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene may affect folate metabolism in infants. OBJECTIVES: We investigated the association between infant's MTHFR C677T genotype, the dietary folate source, and concentrations of folate markers in the blood. METHODS: We studied 110 breastfed infants (reference) and 182 infants who were randomly assigned to receive infant...
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