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Article

Identification of new candidate drugs for primary Sjögren’s syndrome using a drug repurposing transcriptomic approach

2 Mar 2023

Abstract excerpt

OBJECTIVES: To date, no immunomodulatory drug has demonstrated its efficacy in primary SS (pSS). We sought to analyse potential commonalities between pSS transcriptomic signatures and signatures of various drugs or specific knock-in or knock-down genes. METHODS: Gene expression from peripheral blood samples of patients with pSS was compared with that of healthy controls in two cohorts and three public databases....

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PMID: 36869684
DOI: 10.1093/rheumatology/kead096

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