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Tumor microenvironment of Burkitt lymphoma: different immune signatures with different clinical behavior

11 Jun 2024

Abstract excerpt

ABSTRACT: Burkitt lymphoma (BL) is characterized by a tumor microenvironment (TME) in which macrophages represent the main component, determining a distinct histological appearance known as "starry sky" pattern. However, in some instances, BL may exhibit a granulomatous reaction that has been previously linked to favorable prognosis and spontaneous regression. The aim of our study was to deeply characterize the...

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PMID: 38861355
DOI: 10.1182/bloodadvances.2023011506

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