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Article

[Circular RNA circRSF1 binds to HuR to promote radiation-induced inflammatory phenotype in hepatic stellate cells].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 20 Jan 2023

Zhou P, Cheng B, Sun Y, Wu D, Chen Y

Abstract excerpt

OBJECTIVE: To investigate whether circular RNA circRSF1 regulates radiation-induced inflammatory phenotype of hepatic stellate cells (HSCs) by binding to HuR protein and repressing its function. METHODS: Human HSC cell line LX2 with HuR overexpression or knockdown was exposed to 8 Gy X-ray irradiation, and the changes in the expression of inflammatory factors (IL-1β, IL-6 and TNF-α) were detected by qRT-PCR. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36856209
DOI: 10.12122/j.issn.1673-4254.2023.01.06
PMCID: PMC9978731

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