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Article

Genetic and non-genetic animal models for autism spectrum disorders (ASD).

Reproductive toxicology (Elmsford, N.Y.) - 1 Sept 2016

Ergaz Zivanit, Weinstein-Fudim Liza, Ornoy Asher

Abstract excerpt

Autism spectrum disorder (ASD) is associated, in addition to complex genetic factors, with a variety of prenatal, perinatal and postnatal etiologies. We discuss the known animal models, mostly in mice and rats, of ASD that helps us to understand the etiology, pathogenesis and treatment of human ASD. We describe only models where behavioral testing has shown autistic like behaviors. Some genetic models mimic known...

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PMID: 27142188
DOI: 10.1016/j.reprotox.2016.04.024

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