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Involvement of the MGF 110-11L Gene in the African Swine Fever Replication and Virulence

14 Apr 2023

Abstract excerpt

) population. To date, no effective and safe vaccines have been marketed against ASF. A starting point for vaccine development is using naturally occurring attenuated strains as a vaccine base. Here, we aimed to remove the multigene family (MGF) 110 gene of unknown function from the Lv17/WB/Rie1 genome to improve the usability of the virus as a live-attenuated vaccine, reducing unwanted side effects. The MGF...

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PMID: 37112759
DOI: 10.3390/vaccines11040846

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