LRT-CLUSTER: A New Clustering Algorithm Based on Likelihood Ratio Test to Identify Driving Genes.

Abstract excerpt

Somatic mutations often occur at high relapse sites in protein sequences, which indicates that the location clustering of somatic missense mutations can be used to identify driving genes. However, the traditional clustering algorithm has such problems as the background signal over-fitting, the clustering algorithm is not suitable for mutation data, and the performance of identifying low-frequency mutation genes...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Cluster Analysis
• Share to Computer Simulation