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Article

Fiji-Based Tool for Rapid and Unbiased Analysis of SA-β-Gal Activity in Cultured Cells.

Biomolecules - 14 Feb 2023

Krzystyniak Adam, Gluchowska Agata, Mosieniak Grazyna, Sikora Ewa

Abstract excerpt

Normal cells under stressful conditions such as DNA damage or excessive mitogenic signaling may undergo senescence, which is associated with cell cycle arrest and induction of a proinflammatory phenotype. Accumulation of senescent cells may contribute to the shortening of the life span by accelerating aging and promoting chronic diseases. Cytochemical detection of the senescence-associated β-galactosidase...

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PMID: 36830731
DOI: 10.3390/biom13020362
PMCID: PMC9953415

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