A Fully-Automated Senescence Test (FAST) for the high-throughput quantification of senescence-associated markers

Abstract excerpt

Abstract Cellular senescence is a major driver of aging and age-related diseases. Quantification of senescent cells remains challenging due to the lack of senescence-specific markers and generalist, unbiased methodology. Here, we describe the Fully-Automated Senescence Test (FAST), an image-based method for the high-throughput, single-cell assessment of senescence in cultured cells. FAST quantifies three of the...

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• Share to Advanced biosensing and bioanalysis techniques
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• Share to Telomeres, Telomerase, and Senescence