Article
Techniques to Induce and Quantify Cellular Senescence.
Journal of visualized experiments : JoVE - 1 May 2017
Noren Hooten Nicole, Evans Michele K
Abstract excerpt
In response to cellular stress or damage, proliferating cells can induce a specific program that initiates a state of long-term cell-cycle arrest, termed cellular senescence. Accumulation of senescent cells occurs with organismal aging and through continual culturing in vitro. Senescent cells influence many biological processes, including embryonic development, tissue repair and regeneration, tumor suppression,...
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