miR-6076 rs1463411 polymorphisms are associated with bleeding during clopidogrel treatment in patients with acute coronary syndrome.

doi:10.1186/s40001-023-01068-9

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Article

miR-6076 rs1463411 polymorphisms are associated with bleeding during clopidogrel treatment in patients with acute coronary syndrome.

European journal of medical research - 24 Feb 2023

Mo Zhen-Zhen, Yuan Zhen, Peng Yuan-Yuan, Zhou Wan-Lu, Dai Wei, Wang Guo, Tang Jie, Zhang Wei, Chen Bi-Lian

Abstract excerpt

Bleeding is a major adverse event during clopidogrel treatment in patients with acute coronary syndrome (ACS). However, the potential mechanism affecting bleeding among individuals is unclear. Herein, we investigated the involvement of CYP2C19*2 and CYP2C19*3, as well as 10 miRNA polymorphisms, in bleeding in Chinese patients with ACS during the first year of clopidogrel treatment. The miR-6076 rs1463411 G...

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PMID: 36829258
DOI: 10.1186/s40001-023-01068-9
PMCID: PMC9951409

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