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Article

Body weight, CYP2C19, and P2Y12 receptor polymorphisms relate to clopidogrel resistance in a cohort of Chinese ischemic stroke patients with aspirin intolerance.

European journal of clinical pharmacology - 1 Nov 2020

Li Zhiqiang, Dong Wanqing, Yang Daorong, Sun Linhai, He Xianjun, Hu Huanhuan, Zhang Jianping, Wang Chunyu, Li Yulin, Zhao Ming, Kong Yu, Wang Yan

Abstract excerpt

PURPOSE: Dual antiplatelet therapy (DAT) with clopidogrel and aspirin is not suitable for clopidogrel resistance (CR) patients with aspirin intolerance. To investigate the prevalence of CR in patients with aspirin intolerance after ischemic stroke (IS) and to assess the relationship between CR and CYP2C19, P2Y12 receptor genotypes in patients with aspirin intolerance after IS. METHODS: We enrolled 126 IS patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32632713
DOI: 10.1007/s00228-020-02946-5

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