Article
Impact of genetic variants on major bleeding after percutaneous coronary intervention based on a prospective multicenter registry.
Scientific reports - 19 Jan 2021
Cha Jung-Joon, Joo Hyung Joon, Park Jae Hyoung, Hong Soon Jun, Ahn Tae Hoon, Kim Byeong-Keuk, Shin WonYong, Ahn Sung Gyun, Yoon JungHan, Kim Yong Hoon, Cho Yun-Hyeong, Kang Woong Chol, Kim Weon, Lim Young-Hyo, Gwon HyeonCheol, Choi WoongGil, Lim Do-Sun
Abstract excerpt
Although dual antiplatelet therapy is essential for patients who undergo percutaneous coronary interventions, the risk of bleeding remains an unsolved problem, and there is limited information on the potential relationship between genetic variants and major bleeding. We analyzed the correlations between four major single nucleotide polymorphisms (CYP2C19, ABCB1, PON1, and P2Y12 G52T polymorphisms) and clinical...
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