Article
Emerging therapies for mitochondrial disorders.
Brain : a journal of neurology - 1 Jun 2016
Nightingale Helen, Pfeffer Gerald, Bargiela David, Horvath Rita, Chinnery Patrick F
Abstract excerpt
Mitochondrial disorders are a diverse group of debilitating conditions resulting from nuclear and mitochondrial DNA mutations that affect multiple organs, often including the central and peripheral nervous system. Despite major advances in our understanding of the molecular mechanisms, effective treatments have not been forthcoming. For over five decades patients have been treated with different vitamins,...
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