Article
KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease.
European journal of human genetics : EJHG - 1 Nov 2023
Boulogne Floranne, Claus Laura R, Wiersma Henry, Oelen Roy, Schukking Floor, de Klein Niek, Li Shuang, Westra Harm-Jan, van der Zwaag Bert, van Reekum Franka, Sierks Dana, Schönauer Ria, Li Zhigui, Bijlsma Emilia K, Bos Willem Jan W, Halbritter Jan, Knoers Nine V A M, Besse Whitney, Deelen Patrick, Franke Lude, van Eerde Albertien M
Abstract excerpt
Genetic testing in patients with suspected hereditary kidney disease may not reveal the genetic cause for the disorder as potentially pathogenic variants can reside in genes that are not yet known to be involved in kidney disease. We have developed KidneyNetwork, that utilizes tissue-specific expression to inform candidate gene prioritization specifically for kidney diseases. KidneyNetwork is a novel method...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.