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C→U transition biases in SARS-CoV-2: still rampant 4 years from the start of the COVID-19 pandemic

30 Oct 2024

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ABSTRACT The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the pandemic and post-pandemic periods has been characterized by rapid adaptive changes that confer immune escape and enhanced human-to-human transmissibility. Sequence change is additionally marked by an excess number of C→U transitions suggested as being due to host-mediated genome editing. To investigate how these...

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PMID: 39475243
DOI: 10.1128/mbio.02493-24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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