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The role of FOXA family transcription factors in glucolipid metabolism and NAFLD

31 Jan 2023

Abstract excerpt

Abnormal glucose metabolism and lipid metabolism are common pathological processes in many metabolic diseases, such as nonalcoholic fatty liver disease (NAFLD). Many studies have shown that the forkhead box (FOX) protein subfamily FOXA has a role in regulating glucolipid metabolism and is closely related to hepatic steatosis and NAFLD. FOXA exhibits a wide range of functions ranging from the initiation steps of...

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PMID: 36798663
DOI: 10.3389/fendo.2023.1081500

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