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Article

Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease

9 Jul 2020

Abstract excerpt

Obesity is the primary risk factor for the pathogenesis of non-alcoholic fatty liver disease (NAFLD), the worldwide prevalence of which continues to increase dramatically. The liver plays a pivotal role in the maintenance of whole-body lipid and glucose homeostasis. This is mainly mediated by the transcriptional activation of hepatic pathways that promote glucose and lipid production or utilization in response to...

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PMID: 32660130
DOI: 10.3390/metabo10070283

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