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Human cytomegalovirus infection perturbs neural progenitor cell fate via the expression of viral microRNAs

1 Feb 2023

Abstract excerpt

Human cytomegalovirus (HCMV) preferentially targets neural progenitor cells (NPCs) in congenitally infected fetal brains, inducing neurodevelopmental disorders. While HCMV expresses several microRNAs (miRNAs) during infection, their roles in NPC infection are unclear. Here, we characterized expression of cellular and viral miRNAs in HCMV-infected NPCs during early infection by microarray and identified seven...

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PMID: 36772841
DOI: 10.1002/jmv.28574

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