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Article

The clinical impact of pharmacogenetics on the treatment of epilepsy.

Epilepsia - 1 Jan 2009

Löscher Wolfgang, Klotz Ulrich, Zimprich Fritz, Schmidt Dieter

Abstract excerpt

Drug treatment of epilepsy is characterized by unpredictability of efficacy, adverse drug reactions, and optimal doses in individual patients, which, at least in part, is a consequence of genetic variation. Since genetic variability in drug metabolism was reported to affect the treatment with phenytoin more than 25 years ago, the ultimate goal of pharmacogenetics is to use the genetic makeup of an individual to...

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Identifiers

PMID: 18627414
DOI: 10.1111/j.1528-1167.2008.01716.x

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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