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Article

Genetic Predisposition to Colorectal Cancer: How Many and Which Genes to Test?

International journal of molecular sciences - 21 Jan 2023

Rebuzzi Francesca, Ulivi Paola, Tedaldi Gianluca

Abstract excerpt

Colorectal cancer is one of the most common tumors, and genetic predisposition is one of the key risk factors in the development of this malignancy. Lynch syndrome and familial adenomatous polyposis are the best-known genetic diseases associated with hereditary colorectal cancer. However, some other genetic disorders confer an increased risk of colorectal cancer, such as Li-Fraumeni syndrome (TP53 gene),...

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Identifiers

PMID: 36768460
DOI: 10.3390/ijms24032137
PMCID: PMC9916931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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