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Article

Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis

10 Feb 2023

Abstract excerpt

Abstract Background Pregnancy in women with multiple sclerosis (wwMS) is associated with a reduction of long-term disability progression. The mechanism that drives this effect is unknown, but converging evidence suggests a role for epigenetic mechanisms altering immune and/or central nervous system function. In this study, we aimed to identify whole blood and immune cell-specific DNA methylation patterns...

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PMID: 36765422
DOI: 10.1186/s13148-023-01438-4

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