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Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma

10 Feb 2023

Abstract excerpt

BACKGROUND: Cell-cell communications of various cell populations within tumor microenvironment play an essential role in primary tumor growth, metastasis evolution, and immune escape. Nevertheless, comprehensive investigation of cell-cell communications in the ccRCC (Clear cell renal carcinoma) microenvironment and how this interplay affects prognosis still remains limited. METHODS: Intercellular communications...

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PMID: 36765369
DOI: 10.1186/s12967-022-03858-x

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