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Article

The developmental basis of fingerprint pattern formation and variation

9 Feb 2023

Abstract excerpt

Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint ridge formation and their intricate arrangements are unknown. Here we show that fingerprint ridges are epithelial structures that undergo a truncated hair follicle developmental program and fail to recruit a mesenchymal condensate. Their spatial pattern is...

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Identifiers

PMID: 36764291
DOI: 10.1016/j.cell.2023.01.015

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