Article
Limb development genes underlie variation in human fingerprint patterns.
Cell - 6 Jan 2022
Li Jinxi, Glover James D, Zhang Haiguo, Peng Meifang, Tan Jingze, Mallick Chandana Basu, Hou Dan, Yang Yajun, Wu Sijie, Liu Yu, Peng Qianqian, Zheng Shijie C, Crosse Edie I, Medvinsky Alexander, Anderson Richard A, Brown Helen, Yuan Ziyu, Zhou Shen, Xu Yanqing, Kemp John P, Ho Yvonne Y W, Loesch Danuta Z, Wang Lizhong, Li Yingxiang, Tang Senwei, Wu Xiaoli, Walters Robin G, Lin Kuang, Meng Ruogu, Lv Jun, Chernus Jonathan M, Neiswanger Katherine, Feingold Eleanor, Evans David M, Medland Sarah E, Martin Nicholas G, Weinberg Seth M, Marazita Mary L, Chen Gang, Chen Zhengming, Zhou Yong, Cheeseman Michael, Wang Lan, Jin Li, Headon Denis J, Wang Sijia
Abstract excerpt
Fingerprints are of long-standing practical and cultural interest, but little is known about the mechanisms that underlie their variation. Using genome-wide scans in Han Chinese cohorts, we identified 18 loci associated with fingerprint type across the digits, including a genetic basis for the long-recognized "pattern-block" correlations among the middle three digits. In particular, we identified a variant near...
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