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Article

Integration of genome-wide association study and expression quantitative trait loci data identifies AIM2 as a risk gene of periodontitis.

Journal of clinical periodontology - 1 May 2020

Li Wenjing, Zheng Qiwen, Meng Huanxin, Chen Dafang

Abstract excerpt

AIM: To identify risk variants associated with gene expression in peripheral blood and to identify genes whose expression change may contribute to the susceptibility to periodontitis. MATERIAL AND METHODS: We systematically integrated the genetic associations from a recent large-scale periodontitis GWAS and blood expression quantitative trait loci (eQTL) data using Sherlock, a Bayesian statistical framework. We...

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PMID: 32031269
DOI: 10.1111/jcpe.13268

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