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Article

A large candidate-gene association study suggests genetic variants at IRF5 and PRDM1 to be associated with aggressive periodontitis.

Journal of clinical periodontology - 1 Dec 2014

Schaefer Arne S, Jochens Arne, Dommisch Henrik, Graetz Christian, Jockel-Schneider Yvonne, Harks Inga, Staufenbiel Ingmar, Meyle Joerg, Eickholz Peter, Folwaczny Mathias, Laine Marja, Noack Barbara, Wijmenga Cisca, Lieb Wolfgang, Bruckmann Corinna, Schreiber Stefan, Jepsen Søren, Loos Bruno G

Abstract excerpt

AIM: Epidemiological and clinical studies indicated a relationship of periodontitis with rheumatoid arthritis (RA). We aimed to identify shared genetic susceptibility loci of RA and periodontitis. MATERIALS AND METHODS: Forty-seven risk genes of genome-wide significance of RA and SLE were genotyped in a German case-control sample of aggressive periodontitis (AgP), using Immunochip genotyping arrays (Illumina, 600...

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Identifiers

PMID: 25263394
DOI: 10.1111/jcpe.12314

Genes

PRDM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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