Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of genome-wide DNA methylation and polymorphisms in periodontitis etiology: A narrative review.

Biomolecules & biomedicine - 3 Jul 2025

Jovanova Elena, Angjelova Angela, Polizzi Alessandro, Isola Gaetano

Abstract excerpt

Periodontitis is a multifactorial inflammatory disease influenced by genetic, epigenetic, and environmental factors. Recent advancements in genomic and epigenomic research have highlighted the role of genetic polymorphisms and genome-wide DNA methylation in its pathogenesis. DNA methylation regulates gene expression, affecting immune responses and inflammatory pathways, while genetic polymorphisms may predispose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Epigenesis, Genetic
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Periodontitis

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 40613578
DOI: 10.17305/bb.2025.12646
PMCID: PMC12834309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of genome-wide DNA methylation and polymorphisms in periodontitis etiology: A narrative review.PMID 40613578Read ↗

Epigenetic modifications as a biomarker for periodontitis and peri-implantitis: a reviewSemantic proximity Read ↗

The Relevance of DNA Methylation and Histone Modification in Periodontitis: A Scoping ReviewSemantic proximity Read ↗

The Potential Role of Epigenetic Modifications on Different Facets in the Periodontal PathogenesisSemantic proximity Read ↗

Modifiable risk factors in periodontal diseaseSemantic proximity Read ↗

Targeting epigenetic mechanisms in periodontal diseases.Semantic proximity Read ↗

Periodontal disease: a genetic perspective.Semantic proximity Read ↗

Current Concepts of Epigenetics and Its Role in PeriodontitisSemantic proximity Read ↗

Epigenetic reprogramming in periodontal disease: Dynamic crosstalk with potential impact in oncogenesisSemantic proximity Read ↗

Genetics of periodontitis: Discovery, biology, and clinical impact.Semantic proximity Read ↗

Epigenome-wide association study using peripheral blood leukocytes identifies genomic regions associated with periodontal disease and edentulism in the Atherosclerosis Risk in Communities StudySemantic proximity Read ↗

The role of inflammation and genetics in periodontal diseaseSemantic proximity Read ↗

Identification of inflammation-related DNA methylation biomarkers in periodontitis patients based on weighted co-expression analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.