Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness.

Investigative ophthalmology & visual science - 1 Feb 2023

Fenner Beau J, Li Hengtong, Gan Alfred T L, Song Young Seok, Tham Yih Chung, Jonas Jost B, Wang Ya Xing, Cheng Ching Yu, Wong Tien Yin, Teo Kelvin Y C, Tan Anna C S, Fan Qiao, Cheung Chui Ming Gemmy

Abstract excerpt

Purpose: To identify genetic alleles associated with differences in choroidal thickness (CT) in a population-based multiethnic Asian cohort. Methods: A population-based multiethnic Asian cohort without retinal pathology was subjected to spectral-domain OCT (SD-OCT) and genotyping of risk alleles in CFH, VIPR2, ARMS2, and CETP. Subfoveal choroidal thickness (SFCT) values were assessed from SD-OCT, and associations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choroid
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethnicity

Share to Macular Degeneration

Share to Polymorphism, Single Nucleotide

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 36749597
DOI: 10.1167/iovs.64.2.10
PMCID: PMC9919691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness.PMID 36749597Read ↗

Thickness of retina and choroid in the elderly population and its association with Complement Factor H polymorphism: KLoSHA Eye studySemantic proximity Read ↗

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.Semantic proximity Read ↗

Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians.Semantic proximity Read ↗

Rare complement factor I variants associated with reduced macular thickness and age-related macular degeneration in the UK Biobank.Semantic proximity Read ↗

Common variants in the complement factor H gene confer genetic susceptibility to central serous chorioretinopathy.Semantic proximity Read ↗

T and genetic variations between Asian and Caucasian polypoidal choroidal vasculopathy.Semantic proximity Read ↗

CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy.Semantic proximity Read ↗

Systemic, Ocular and Genetic Risk Factors for Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Singaporeans.Semantic proximity Read ↗

Lens status influences the association between CFH polymorphisms and age-related macular degeneration: findings from two population-based studies in Singapore.Semantic proximity Read ↗

Impact of age-related maculopathy susceptibility 2, high-temperature requirement A serine peptidase 1, and complement factor H genetic variants on clinical phenotypes of age-related macular degeneration.Semantic proximity Read ↗

Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypesSemantic proximity Read ↗

Systematic review and meta-analysis of the association between complement factor H I62V polymorphism and risk of polypoidal choroidal vasculopathy in Asian populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.