CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy.

doi:10.1073/pnas.1802212115

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Article

CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy.

Proceedings of the National Academy of Sciences of the United States of America - 12 Jun 2018

Hosoda Yoshikatsu, Yoshikawa Munemitsu, Miyake Masahiro, Tabara Yasuharu, Ahn Jeeyun, Woo Se Joon, Honda Shigeru, Sakurada Yoichi, Shiragami Chieko, Nakanishi Hideo, Oishi Akio, Ooto Sotaro, Miki Akiko, Iida Tomohiro, Iijima Hiroyuki, Nakamura Makoto, Khor Chiea Chuen, Wong Tien Yin, Song Kyuyoung, Park Kyu Hyung, Yamada Ryo, Matsuda Fumihiko, Tsujikawa Akitaka, Yamashiro Kenji

Abstract excerpt

Central serous chorioretinopathy (CSC) is a common disease affecting younger people and may lead to vision loss. CSC shares phenotypic overlap with age-related macular degeneration (AMD). As recent studies have revealed a characteristic increase of choroidal thickness in CSC, we conducted a genome-wide association study on choroidal thickness in 3,418 individuals followed by TaqMan assays in 2,692 subjects, and...

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Identifiers

PMID: 29844195
DOI: 10.1073/pnas.1802212115
PMCID: PMC6004488

Genes

CFH
VIPR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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