Article
Lens status influences the association between CFH polymorphisms and age-related macular degeneration: findings from two population-based studies in Singapore.
PloS one - 1 Jan 2015
Wong Chee Wai, Liao Jiemin, Cheung Gemmy C, Khor Chiea Chuen, Vithana Eranga N, Wang Jie Jin, Mitchell Paul, Aung Tin, Wong Tien Y, Cheng Ching-Yu
Abstract excerpt
AIMS: To determine the differential effects of genetic polymorphism in CFH and ARMS2 on risk of age-related macular degeneration (AMD) between phakic vs. pseudophakic/aphakic eyes. METHODS: 9,529 eyes of 4,918 participants from the Singapore Malay Eye Study and Singapore Indian Eye Study were analyzed. Participants had detailed eye examinations, including slit-lamp examinations and dilated fundus photography. AMD...
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