Article
The association of blood ctDNA levels to mutations of marker genes in colorectal cancer.
Cancer reports (Hoboken, N.J.) - 1 Apr 2023
Bai Fei, Du Qian, Zou Qingliang, Xu Lin, Dong Wei, Lv Xinlin, Han Xiaorong, Zhou Huijun, Zhang Chi, Lu Tao
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is a deadly and commonly diagnosed cancer. Cell-free circulating tumor DNAs (ctDNA) have been used in the diagnosis and treatment of CRC, but there are open questions about the relationship between ctDNAs and CRC. Although mutations of genes detected by ctDNA in CRC have been studied, the quantitative relationship between ctDNA mutations and ctDNA concentration has not been...
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