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Article

Tankyrase 1 polymorphism associated with an increased risk in developing non-small cell lung cancer in a Chinese population: a proof-of-principle study.

International journal of clinical and experimental pathology - 1 Jan 2015

Wang Ying, Jiang Weiyu, Liu Xiaogu, Zhang Yongjun

Abstract excerpt

OBJECTIVES: Tankyrase 1 (TNKS1), a poly (ADP-ribose) polymerase, regulates telomere length and apoptosis in cells, overexpression of which occurred in non-small cell lung cancer (NSCLC). This study investigated TNKS1 single-nucleotide polymorphisms (SNPs) for association with a risk in NSCLC development in a Chinese population. METHODS: NSCLC cases and healthy controls of 500 each were recruited for genotyping of...

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PMID: 26617760
PMCID: PMC4637575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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