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Reduced platelet 5-HT content is associated with rest tremor in Parkinson's disease.

Parkinsonism & related disorders - 1 Mar 2023

Wang Jian-Yong, Chen Jin-Yu, Lian Yi-Zhi, Zhang Wen-Yuan, Wang Meng-Yan, Liu Rong-Pei, Chen Ling-Hao, Zhang Xiong, Zhu Jian-Hong

Abstract excerpt

INTRODUCTION: Parkinson's disease (PD) is highly heterogeneous in manifestations and pathogenesis. Serotonergic neurotransmitter system dysfunction is frequently implicated in PD tremor. Serotonin (5-HT) content in platelets is highly correlated with that in cerebrospinal fluid. In this study, we aimed to understand whether and how platelet 5-HT content reflects tremor in PD. METHOD: A total of 139 Chinese PD...

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PMID: 36739793
DOI: 10.1016/j.parkreldis.2023.105314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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