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Article

Derivation and Validation of Clinical Phenotypes of the Cardiopulmonary Bypass-Induced Inflammatory Response.

Anesthesia and analgesia - 1 Mar 2023

Milam Adam J, Liang Chen, Mi Junhui, Mascha Edward J, Halvorson Sven, Yan Manshu, Soltesz Edward, Duncan Andra E

Abstract excerpt

BACKGROUND: Precision medicine aims to change treatment from a "one-size-fits-all" approach to customized therapies based on the individual patient. Applying a precision medicine approach to a heterogeneous condition, such as the cardiopulmonary bypass (CPB)-induced inflammatory response, first requires identification of homogeneous subgroups that correlate with biological markers and postoperative outcomes. As a...

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PMID: 36730794
DOI: 10.1213/ANE.0000000000006247

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