Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis.

doi:10.1097/EJA.0000000000000846

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Article

Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis.

European journal of anaesthesiology - 1 Sept 2018

Serpa Neto Ary, Bos Lieuwe D, Campos Pedro P Z A, Hemmes Sabrine N T, Bluth Thomas, Calfee Carolyn S, Ferner Marion, Güldner Andreas, Hollmann Markus W, India Inmaculada, Kiss Thomas, Laufenberg-Feldmann Rita, Sprung Juraj, Sulemanji Demet, Unzueta Carmen, Vidal Melo Marcos F, Weingarten Toby N, Tuip-de Boer Anita M, Pelosi Paolo, Gama de Abreu Marcelo, Schultz Marcus J

Abstract excerpt

BACKGROUND: Biological phenotypes have been identified within several heterogeneous pulmonary diseases, with potential therapeutic consequences. OBJECTIVE: To assess whether distinct biological phenotypes exist within surgical patients, and whether development of postoperative pulmonary complications (PPCs) and subsequent dependence of intra-operative positive end-expiratory pressure (PEEP) differ between such...

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PMID: 29957706
DOI: 10.1097/EJA.0000000000000846

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