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Article

Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis.

Thorax - 1 Oct 2017

Bos L D, Schouten L R, van Vught L A, Wiewel M A, Ong D S Y, Cremer O, Artigas A, Martin-Loeches I, Hoogendijk A J, van der Poll T, Horn J, Juffermans N, Calfee C S, Schultz M J

Abstract excerpt

RATIONALE: We hypothesised that patients with acute respiratory distress syndrome (ARDS) can be clustered based on concentrations of plasma biomarkers and that the thereby identified biological phenotypes are associated with mortality. METHODS: Consecutive patients with ARDS were included in this prospective observational cohort study. Cluster analysis of 20 biomarkers of inflammation, coagulation and endothelial...

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Identifiers

PMID: 28450529
DOI: 10.1136/thoraxjnl-2016-209719
PMCID: PMC5964254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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