Article
Prolonged SARS-CoV-2 Infection and Intra-Patient Viral Evolution in an Immunodeficient Child.
The Pediatric infectious disease journal - 1 Mar 2023
Filippi Micheli, Ribeiro Amorim Mariene, Soares da Silva Mariana, Schons Gularte Juliana, Demoliner Meriane, Girardi Viviane, de Abreu Goes Pereira Vyctoria Malayhka, Witt Hansen Alana, Fleck Juliane Deise, Frohlich Júlia, de-Paris Fernanda, Motta Rodrigues Grazielle, Aparecida Risczik Arruda Correa Janaina, Machado Arlindo De Mattos Elissandra, Minuto Paiva Rodrigo, Deutschendorf Caroline, Soares Falcetta Frederico, Proença Modena José Luiz, Rosado Spilki Fernando
Abstract excerpt
BACKGROUND: With the progression of the Coronavirus disease pandemic, the number of mutations in the viral genome has increased, showing the adaptive evolution of severe acute respiratory syndrome coronavirus 2 in humans and intensification in transmissibility. Long-term infections also allow the development of viral diversity. In this study, we report the case of a child with severe combined immu presenting a...
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