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Article

Novel Genetic Variants Associated with Chronic Kidney Disease Progression.

Journal of the American Society of Nephrology : JASN - 1 May 2023

Han Miyeun, Moon Sungji, Lee Sangjun, Kim Kyungsik, An Woo Ju, Ryu Hyunjin, Kang Eunjeong, Ahn Jung-Hyuck, Sung Hye Youn, Park Yong Seek, Lee Seung Eun, Lee Sang-Ho, Jeong Kyung Hwan, Ahn Curie, Kelly Tanika N, Hsu Jesse Y, Feldman Harold I, Park Sue K, Oh Kook-Hwan

Abstract excerpt

SIGNIFICANCE STATEMENT: eGFR slope has been used as a surrogate outcome for progression of CKD. However, genetic markers associated with eGFR slope among patients with CKD were unknown. We aimed to identify genetic susceptibility loci associated with eGFR slope. A two-phase genome-wide association study identified single nucleotide polymorphisms (SNPs) in TPPP and FAT1-LINC02374 , and 22 of them were used to...

Topics

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Cohort Studies
Disease Progression
Genetic Markers
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Polymorphism, Single Nucleotide

Quantitative Trait Loci

Renal Insufficiency, Chronic

Source

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Identifiers

PMID: 36720675
DOI: 10.1681/ASN.0000000000000066
PMCID: PMC10125649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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