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Bone Formation in 2D Culture of Primary Cells

11 Nov 2022

Abstract excerpt

ABSTRACT Relevance of mineralized nodules in two‐dimensional (2D) osteoblast/osteocyte cultures to bone biology, pathology, and engineering is a decades old question, but a comprehensive answer appears to be still wanting. Bone‐like cells, extracellular matrix (ECM), and mineral were all reported but so were non‐bone‐like ones. Many studies described seemingly bone‐like cell‐ECM structures based on similarity to...

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PMID: 36699640
DOI: 10.1002/jbm4.10701

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