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Article

Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo.

PLoS pathogens - 1 Jul 2006

Nobile Clarissa J, Andes David R, Nett Jeniel E, Smith Frank J, Yue Fu, Phan Quynh-Trang, Edwards John E, Filler Scott G, Mitchell Aaron P

Abstract excerpt

The fungal pathogen Candida albicans is frequently associated with catheter-based infections because of its ability to form resilient biofilms. Prior studies have shown that the transcription factor Bcr1 governs biofilm formation in an in vitro catheter model. However, the mechanistic role of the Bcr1 pathway and its relationship to biofilm formation in vivo are unknown. Our studies of biofilm formation in vitro...

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Identifiers

PMID: 16839200
DOI: 10.1371/journal.ppat.0020063
PMCID: PMC1487173

Genes

ECE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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