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Article

Risk single-nucleotide polymorphism-mediated enhancer-promoter interaction drives keloids through long noncoding RNA down expressed in keloids.

The British journal of dermatology - 23 Jan 2023

Deng Cheng-Cheng, Zhang Li-Xue, Xu Xue-Yan, Zhu Ding-Heng, Cheng Qing, Ma Shufeng, Rong Zhili, Yang Bin

Abstract excerpt

BACKGROUND: Keloids represent one extreme of aberrant dermal wound healing and are characterized by fibroblast hyperproliferation and excessive deposition of extracellular matrix. Genetics is a major factor for predisposition to keloids and genome-wide association study has identified a single-nucleotide polymorphism (SNP) rs873549 at 1q41 as a susceptibility locus. The SNP rs873549, and the SNPs in strong...

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PMID: 36689521
DOI: 10.1093/bjd/ljac025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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