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Article

The epigenetics of keloids

21 Jun 2021

Abstract excerpt

Keloid scarring is a fibroproliferative disorder of the skin with unknown pathophysiology, characterised by fibrotic tissue that extends beyond the boundaries of the original wound. Therapeutic options are few and commonly ineffective, with keloids very commonly recurring even after surgery and adjunct treatments. Epigenetics, defined as alterations to the DNA not involving the base-pair sequence, is a key...

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PMID: 34152651
DOI: 10.1111/exd.14414

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